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Mechanical design and analysis of a novel variable stiffness actuator with symmetrical pivot adjustment

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 4,   Pages 711-725 doi: 10.1007/s11465-021-0647-1

Abstract: Thus, this paper aims to design a novel variable stiffness actuator (VSA) that can provide safer physicalVSA follows the idea of modular design, mainly including a variable stiffness module and a drive moduleThe variable stiffness module transmits the motion from the drive module in a roundabout manner, makingAs the key component of the variable stiffness module, a stiffness adjustment mechanism with a symmetricalExperiment results show that the VSA stiffness is close to the theoretical design stiffness.

Keywords： variable stiffness actuator     variable stiffness module     drive module     symmetrical structure     double-deck    

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The Fibrillar Matrix: Novel Avenues for Breast Cancer Detection and Treatment Review

Rasha Rezk,  Raquel Marín-García,  Annica K.B.Gad

Engineering 2021, Volume 7, Issue 10,   Pages 1375-1380 doi: 10.1016/j.eng.2021.04.024

Abstract: These fibers increase the mechanical stiffness of the tissue, which has long been used for tumor diagnosisoverview of how the mechanical properties of breast tumor tissues differ from those of normal breast tissueWe also describe how biomaterial models make it possible to understand how the stiffness and viscosity

Keywords： Breast cancer     Tissue stiffness     Cancer metastasis     Cell migration     Bioengineered scaffold     Viscosity    

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Atypical pituitary hormone–target tissue axis

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 1-17 doi: 10.1007/s11684-022-0973-7

Abstract: non-classical organs were summarized, defined by the novel concept of an “atypical pituitary hormone–target tissueThe continued exploration of the physiology of the “atypical pituitary hormone–target tissue axis” could

Keywords： thyroid-stimulating hormone     follicle-stimulating hormone     luteinizing hormone     adrenocorticotrophic hormone     prolactin    

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Progress and perspectives of neural tissue engineering

Xiaosong Gu

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 401-411 doi: 10.1007/s11684-015-0415-x

Abstract: addressed by current therapeutic interventions for these diseases, a novel promising field of neural tissueSeveral important aspects related to tissue engineered nerves, including the theory on their constructionFurthermore, potential research directions for the future development of neural tissue engineering are

Keywords： nerve injury     tissue engineering     nerve grafts    

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The stem cell and tissue engineering research in Chinese ophthalmology

GE Jian, LIU Jingbo

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 6-10 doi: 10.1007/s11684-007-0002-x

Abstract: Much has been considerably developed recently in the ophthalmic research of stem cell (SC) and tissue

Keywords： available     observable     neuroregeneration     protection     function reconstruction    

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Decellularized extracellular matrix mediates tissue construction and regeneration

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 56-82 doi: 10.1007/s11684-021-0900-3

Abstract: Contributing to organ formation and tissue regeneration, extracellular matrix (ECM) constituents providetissue with three-dimensional (3D) structural integrity and cellular-function regulation.prompt stem-cell proliferation and differentiation for 3D organoid construction in vitro or tissueCellular ECM improves 3D culture development in vitro and tissue remodeling during wound healingGaining better insight into ECM derived from either tissue or cells that regulate 3D tissue reconstruction

Keywords： decellularized extracellular matrix     3D culture     organoids     tissue repair    

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Non-closure of the peritoneum and subcutaneous tissue at radical hysterectomy: A randomized controlled

Zhou-Fang XIONG MD, Wei-Hong DONG MD, Ze-Hua WANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 112-116 doi: 10.1007/s11684-010-0016-7

Abstract: conducted a trial to assess the influence of closure or nonclosure of the peritoneum and subcutaneous tissueResults showed that non-closure of the peritoneum and subcutaneous tissue could shorten operation timeOur study revealed that closure of the peritoneum and subcutaneous tissue provides no immediate postoperativeThe practice of closure of the peritoneum and subcutaneous tissue at radical hysterectomy should be questioned

Keywords： cervical cancer     radical surgery     peritoneum     subcutaneous tissue    

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Primary cilia in hard tissue development and diseases

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 657-678 doi: 10.1007/s11684-021-0829-6

Abstract: Hard tissue diseases have a serious effect on human survival and quality of life.mutations present overt changes in the skeletal system, suggesting that primary cilia are involved in hard tissuethrough primary cilia by intraflagellar transport, which affects key signaling pathways during hard tissueIn addition, the cilium-related diseases of hard tissue and the manifestations of mutant cilia in theWe believe that all the findings will help with the intervention and treatment of related hard tissue

Keywords： primary cilia     bone     mechanical sensing     hard tissue     cilium-related bone disease     tooth    

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Comparison of indices for stiffness performance evaluation

Giuseppe CARBONE, Marco CECCARELLI,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 3,   Pages 270-278 doi: 10.1007/s11465-010-0023-z

Abstract: This paper addresses the problem of a numerical evaluation of the stiffness performance for multibodyStiffness indices are computed and compared for a case study.Results are used for comparing the effectiveness of the stiffness indices.

Keywords： robotics     stiffness     performance indices    

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New nonlinear stiffness actuator with predefined torque‒deflection profile

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 1, doi: 10.1007/s11465-022-0721-3

Abstract: A nonlinear stiffness actuator (NSA) could achieve high torque/force resolution in low stiffness rangeand high bandwidth in high stiffness range, both of which are beneficial for physical interaction between

Keywords： compliant actuator     nonlinear stiffness actuator     nonlinear spring     predefined torque−deflection profile    

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Mechanical design, modeling, and identification for a novel antagonistic variable stiffness dexterous

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 3, doi: 10.1007/s11465-022-0691-5

Abstract: It achieves finger stiffness adjustability according to the biologically inspired stiffness variationprinciple of discarding some mobilities to adjust stiffness.The mechanical design of the finger and its stiffness adjusting methods are elaborated.The stiffness characteristics of the finger joint and the actuation unit are analyzed.finger stiffness presets are provided to verify the validity of the model.

Keywords： multifingered hand     mechanism design     robot safety     variable stiffness actuator    

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Mechanical performance analysis and stiffness test of a new type of suspension bridge

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 5,   Pages 1160-1180 doi: 10.1007/s11709-021-0760-6

Abstract: A new type of suspension bridge is proposed based on the gravity stiffness principle.The rigid webs connect the main cable and main girder to form a truss that can improve the bending stiffnessbraces connect the main cables to form a closed space truss structure that can improve the torsional stiffnessA stiffness test was carried out on the new type of suspension bridge with a small span, and the results

Keywords： new type of suspension bridge     stiffness test     mechanical performance     railway bridge     space truss    

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Investigating the influence of delamination on the stiffness of composite pipes under compressive transverse

Sattar MALEKI, Roham RAFIEE, Abolfazl HASANNIA, Mohammad Reza HABIBAGAHI

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 6,   Pages 1316-1323 doi: 10.1007/s11709-019-0555-1

Abstract: The effect of delamination on the stiffness reduction of composite pipes is studied in this research.The stiffness test of filament wound composite pipes is simulated using cohesive zone method.geometrical parameters including delamination size and its position with respect to loading direction on stiffnessAt first, finite element results for stiffness test of a perfect pipe without delamination are validateddirections and also its orientation with respect to loading direction on delamination propagation and stiffness

Keywords： delamination     composite pipes     stiffness test     cohesive zone method    

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A numerical framework for underground structures in layered ground under inclined P-SV waves using stiffness

Frontiers of Structural and Civil Engineering 2023, Volume 17, Issue 1,   Pages 10-24 doi: 10.1007/s11709-022-0904-3

Abstract: The free-field responses are first obtained using the stiffness matrix method based on plane-wave assumptions

Keywords： underground structures     seismic response     stiffness matrix method     domain reduction method     P-SV waves    

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Gear fault diagnosis using gear meshing stiffness identified by gearbox housing vibration signals

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 4, doi: 10.1007/s11465-022-0713-3

Abstract: The gear meshing stiffness (GMS) identification approach is proposed by using housing vibration signalsdiscovered in the identified GMS spectra, and the results also validate the rationality of using meshing stiffness

Keywords： gearbox fault diagnosis     meshing stiffness     identification     transfer path     signal processing    

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Title Author Date Type Operation

Mechanical design and analysis of a novel variable stiffness actuator with symmetrical pivot adjustment

Journal Article

The Fibrillar Matrix: Novel Avenues for Breast Cancer Detection and Treatment

Rasha Rezk,  Raquel Marín-García,  Annica K.B.Gad

Journal Article

Atypical pituitary hormone–target tissue axis

Journal Article

Progress and perspectives of neural tissue engineering

Xiaosong Gu

Journal Article

The stem cell and tissue engineering research in Chinese ophthalmology

GE Jian, LIU Jingbo

Journal Article

Decellularized extracellular matrix mediates tissue construction and regeneration

Journal Article

Non-closure of the peritoneum and subcutaneous tissue at radical hysterectomy: A randomized controlled

Zhou-Fang XIONG MD, Wei-Hong DONG MD, Ze-Hua WANG MD,

Journal Article

Primary cilia in hard tissue development and diseases

Journal Article

Comparison of indices for stiffness performance evaluation

Giuseppe CARBONE, Marco CECCARELLI,

Journal Article

New nonlinear stiffness actuator with predefined torque‒deflection profile

Journal Article

Mechanical design, modeling, and identification for a novel antagonistic variable stiffness dexterous

Journal Article

Mechanical performance analysis and stiffness test of a new type of suspension bridge

Journal Article

Investigating the influence of delamination on the stiffness of composite pipes under compressive transverse

Sattar MALEKI, Roham RAFIEE, Abolfazl HASANNIA, Mohammad Reza HABIBAGAHI

Journal Article

A numerical framework for underground structures in layered ground under inclined P-SV waves using stiffness

Journal Article

Gear fault diagnosis using gear meshing stiffness identified by gearbox housing vibration signals

Journal Article